A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

By Peter Uetz, L. Giot, G. Cagney, T. Mansfield, Richard S. Judson, James R. Knight, D. Lockshon, Vaibhav A. Narayan, Maithreyan Srinivasan, P. Pochart and 10 more. Nature, 2000

4,944 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3416a9e618f42ae68d7788775b68becaa46f6999

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Citations in the corpus

Analyzing and modeling real-world phenomena with complex networks: a survey of applications (2007, methodology): “This limitation has motivated the development of many other methods, including bioc hemical techniques such as affinity [295] and molecular size-based chromatography, affinit y blotting, immuno-precipitation and cross-linking [317, 321, 322, 323].”
Gaining confidence in high-throughput protein interaction networks (2004, neutral): “dtd" [ ]> Protein-protein interactions identified by high-throughput yeast two-hybrid screens (Y2H”
A quantitative protein interaction network for the ErbB receptors using protein microarrays (2006, neutral): “NATURE | Vol 439 | 12 January 2006 ARTICLES either ‘interact’ or ‘don’t interact’ 21–24 .”
Protein analysis on a proteomic scale (2003, background): “In this way, 192 baits were screened against an array of essentially all activation-domain fusions of full-length yeast ORFs to identify 281 putative interaction”
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (2006, background): “Protein–protein interaction networks generated in model organisms such as yeast (Uetz et al., 2000; Ito et al., 2001), worm (Walhout et al.”
Development of human protein reference database as an initial platform for approaching systems biology in humans. (2003, methodology): “…unique protein– protein interactions in HPRD that were derived from individual high-throughput methods such as yeast two-hybrid (Ito et al. 2000; Uetz et al. 2000) and coimmunoprecipitation and mass spectrometry (Gavin et al. 2002; Ho et al. 2002) have been used to systematically identify…”
Integrating 'omic' information: a bridge between genomics and systems biology. (2003, methodology): “Interactome mapping has also been extended to the whole S. cerevisiae proteome [ 37 ,38] and the data obtained have been used to reconstitute modular and proteome-scale interaction networks.”
Molecular characterization of Mycobacterium abscessus strains isolated from a hospital outbreak. (2000, neutral): “Eventually, it may be possible to monitor simultaneously the levels, activities, and interactions of all proteins in the cell (76).”
Functional diversity of protein phosphatase-1, a cellular economizer and reset button. (2004, background): “The latter two proteins have both been found to interact with PP1 in yeast two-hybrid screens (372, 374) and to be components of a complex involved in actin organization, endocytosis, and cell wall morphogenesis (357).”