Understanding nucleotide excision repair and its roles in cancer and ageing

By J. Marteijn, H. Lans, W. Vermeulen, Jan H. J. Hoeijmakers. Nature reviews. Molecular cell biology, 2014

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p53 in the DNA damage repair process (2016, background): “Although this study did not clarify whether the function of p53 in UV resistance was direct or via activities of p53-associated factors, it did lay an important foundation for the further characterization of the functions of p53 in NER (for a detailed review of NER, see Marteijn et al. 2014).”
Mechanisms of DNA damage, repair and mutagenesis (2017, positive): “The subsequent sequence of events is predicted to be the same as in GG-NER as the lesion is removed from the transcribed strand [Marteijn et al., 2014].”
HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B (2015, background): “130 Those relevant for the de-silencing activity of HBx are not known but may yield to the new HBx and cccDNA-dependent infection systems.”
Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution (2024, background): “Notable mechanisms where ROS play a key regulatory role include the circadian clock, as well as DNA repair mechanisms and recently, these interconnections have been studied extensively in various fish models including zebrafish and blind cavefish.”