Biomolecule-sensitive hydrogels.

By T. Miyata, T. Uragami, K. Nakamae. Advanced Drug Delivery Reviews, 2002

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Synthesis, characterization and rheological behavior of pH sensitive poly(acrylamide-co-acrylic acid) hydrogels (2017, background): “However, high water solubility has limited their use as a drug carrier to a certain extent; because of dissolution before the drug can be delivered (Needleman and Smales, 1995).”
pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications (2017, background): “N-succinimidylacrylate based antigen-antibody entrapment hydrogel [13,18]”
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005, background): “Exciting progress has been made in mimicking the proteolytic recognition of natural ECMs in synthetic polymer gels, as examples of a larger class of biomolecule-sensitive network”
Controlled drug delivery in tissue engineering. (2008, background): “In the latter case, external stimuli, such as temperature changes, electric or magnetic fields, ultrasounds and irradiation, activate drug release [122,123].”
Hydrogel nanoparticles in drug delivery. (2008, background): “literature [49–51,53,54,91,92,94,95,63–65].”