The autophagosome: origins unknown, biogenesis complex
By C. Lamb, T. Yoshimori, S. Tooze. Nature reviews. Molecular cell biology, 2013
1,263 citations recorded by the source corpus.
Subfields: Cell Biology, Epidemiology, Physiology
View Paper: https://www.semanticscholar.org/paper/31d98110d9aebb9d7b4e66cb081dc5739c0b11cb
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cell Biology
- N. Mizushima
- Beth Levine
- V. Deretic
- Guido Kroemer
- I. Slaninová
- D. Klionsky
- Douglas R. Green
- Alec C. Kimmelman
In Epidemiology
- Guido Kroemer
- Beth Levine
- N. Mizushima
- I. Slaninová
- D. Klionsky
- V. Deretic
- Douglas R. Green
- L. Galluzzi
In Physiology
- Guido Kroemer
- Beth Levine
- N. Mizushima
- Alec C. Kimmelman
- I. Slaninová
- L. Galluzzi
- V. Deretic
- Douglas R. Green
Citations in the corpus
- Mechanisms of Autophagy Initiation (2017, background): “The membrane supply for phagophore growth can apparently be sourced to a variety of cellular reservoirs (11).”
- Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities. (2017, positive): “WIPI proteins are key autophagic lipid sensors that facilitate autophagosome maturation by bridging PI(3)P production and LC3 lipidation in mammalian cells (Lamb et al., 2013).”
- Molecular definitions of autophagy and related processes (2017, positive): “However, it is efficiently removed by Atg4 family members from the surface of closed autophagosomes (Lamb et al , 2013).”
- Autophagy in malignant transformation and cancer progression (2015, positive): “Autophagosomes derive from so-called phagophores, membranous structures also known as ‘isolation membranes’ whose precise origin remains a matter of debate (Lamb et al , 2013).”
- Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation (2016, background): “Autophagy is a catabolic pathway essential for maintaining cellular homeostasis through lysosome-mediated degradation of cytosolic material (Lamb et al., 2013).”
- Large-scale inference of gene function through phylogenetic annotation of Gene Ontology terms: case study of the apoptosis and autophagy cellular processes (2016, background): “However, this is still a simplified picture of the process since recent studies also showed that contribution from other organelles and membranes such as vesicles derived from the Golgi, plasma membrane and endosomes also contribute to autophago-some expansion (31).”
- WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1 (2014, background): “, 2008), and during autophagosome expansion, membrane from other subcellular compartments (Golgi, mitochondria, and plasma membrane) is probably incorporated (Lamb et al., 2013).”