Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.

By Fiona M Menzies, Angeleen Fleming, A. Caricasole, Carla F. Bento, S. P. Andrews, Avraham Ashkenazi, J. Füllgrabe, Anne Jackson, M. J. Jimenez Sanchez, C. Karabiyik and 12 more. Neuron, 2017

993 citations recorded by the source corpus.

Subfields: Epidemiology, Neurology

View Paper: https://www.semanticscholar.org/paper/001dfcdc3d030b04e5ac355f6fa8167f2bca80d5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. H. Plun-Favreau
2. Paul Denny
3. Henrik Zetterberg
4. David P. Hill
5. Marc Feuermann
6. Paola Roncaglia
7. David M. Wilson
8. M. Cookson

In Neurology

1. Henrik Zetterberg
2. David M. Wilson
3. M. Cookson
4. D. Holtzman
5. L. Van Den Bosch
6. I. Dewachter

Citations in the corpus

• Hallmarks of neurodegenerative diseases. (2023, positive): “129,131 Interestingly, there is a striking parallel in some of the symptoms and aggregating proteins of LSDs with certain NDDs (e.g., tau in NPC).”
• Exploring autophagy with Gene Ontology (2016, background): “phagic clearance of protein aggregates has been presented as a possible contributor to the pathology of Alzheimer disease,(11) Huntington disease,(12) amyotrophic lateral sclerosis(13) and Parkinson disease.(14) Beyond the nervous system, autophagy has”
• Lysosomes as a therapeutic target (2019, background): “Only recently have investigations discov ered that autophagy processes are altered in some of these diseases 59, 62, [126] [127] [128] [129] [130] .”