Passage of inhaled particles into the blood circulation in humans.

By W. Burch. Circulation, 2002

752 citations recorded by the source corpus.

Subfields: Environmental Engineering, Health, Toxicology and Mutagenesis, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/31806f99d24286a97793d642c4dc7e1dea407fca

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In Environmental Engineering

In Health, Toxicology and Mutagenesis

In Pulmonary and Respiratory Medicine

Citations in the corpus

Translocation of Inhaled Ultrafine Particles to the Brain (2004, background): “In contrast, other studies in humans with 99mTc-labeled carbon particles (33 nm) by Brown et al. (2002) did not confirm such uptake into the liver, and the authors cautioned that the findings by Nemmar et al. (2002) were likely due to soluble pertechnetate rather than labeled UFP.”
The Adverse Effects of Air Pollution on the Nervous System (2012, background): “Even though the translocation of inhaled or instilled NPs across the alveolar-capillary barrier has been clearly demonstrated in animal studies for a range of NPs [23, 24], it has been more difficult to directly demonstrate this mechanism in humans [3].”
An Overview of Small Unmanned Aerial Vehicles for Air Quality Measurements: Present Applications and Future Prospectives (2016, background): “They can penetrate and deposit deep inside the lungs [2,41,42] and because their lifetime is longer than particles with a larger diameter, they can be transported further from their sources, due to slow removal from the atmosphere [43].”
A Review on Properties, Opportunities, and Challenges of Transformer Oil-Based Nanofluids (2016, background): “The one way of infiltration of nanoparticles into human body during inhaling can be through nasal cavity [112, 113].”
Potential Role of Ultrafine Particles in Associations between Airborne Particle Mass and Cardiovascular Health (2005, background): “UFPs and associated air toxics translocate to the interstitium and gain entry into the circulation (Nemmar et al. 2002, 2004; Oberdörster et al. 2002).”
Exposure Assessment for Atmospheric Ultrafine Particles (UFPs) and Implications in Epidemiologic Research (2005, background): “Therefore, UFPs may induce pulmonary inflammation at both epithelial and interstitial sites, as well as enter the circulation to reach other target sites, including the cardiovascular system (Nemmar et al. 2002, 2004; Oberdörster 2001; Oberdörster et al. 2002).”
Health effects of particulate air pollution: A review of epidemiological evidence (2011, background): “Unlike larger fine particles, UFP seem to escape phagocytosis by alveolar macrophages and are translocated to extrapulmonary organs (Oberdorster and Utell, 2002), leading to the production of oxygen radicals (Nemmar et al., 2002; Nemmar et al., 2004; Oberdorster et al., 2004; Oberdorster and Utell, ”
Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. (2006, background): “Some NP are characterized by their ability to translocate, from their site of deposition in the lungs to the blood (Nemmar et al., 2001, 2002) and the brain (Oberdorster et al., 2004).”
The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. (2008, background): “A sudden surge in the level of PM has been linked to increased morbidity and mortality due to cardiorespiratory events, including asthma, chronic obstructive pulmonary disease (COPD), and atherosclerosis [1–12].”
Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles (2005, background): “…ambiguous, with one study showing rapid appearance in the blood and significant accumulation of label in the liver of humans inhaling 99Tc-labeled 20-nm carbon particles (Nemmar et al. 2002a), whereas another study using the same labeled particles reported no such accumulation (Brown et al. 2002).”
Toxicology of nanoparticles: A historical perspective (2007, background): “…ultrafine ( 100 nm) particles and detection by g-camera imaging are more controversial, showing either significant translocation to blood and liver (Nemmar et al. 2002) or none (Brown et al. 2002; Mills et al. 2006); this discrepancy is very likely due to uncertainties of the stability of the…”
Nanomaterials and nanoparticles: Sources and toxicity (2007, background): “Most studies show very little or no translocation of radiolabeled polystyrene nanoparticles with diameters of 56!nm and 200 nm [255], or carbon nanoparticles with diameters of 5 nm [256], 4-20 nm [257], 35 nm [259], 100 nm [258], while others show a rapid and substantial translocation into circulati”