Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood.
By I. Weaver, Michael Joseph Meaney, M. Szyf. Proceedings of the National Academy of Sciences of the United States of America, 2006
802 citations recorded by the source corpus.
Subfields: Behavioral Neuroscience, Biological Psychiatry, Social Psychology
View Paper: https://www.semanticscholar.org/paper/30f4abf495614e13ba5103bfe1b13c2b7b4b35dc
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Citations in the corpus
- Prenatal environmental exposures, epigenetics, and disease (2011, positive): “[38,39] showing that maternal stress and subsequent nurturing behaviors alter the epigenotype in rodent offspring, affecting their glucocorticoid receptor (GR) expression and behavior.”
- Long story short: the serotonin transporter in emotion regulation and social cognition (2007, background): “At the molecular level of analysis, life-stress studies should incorporate genome-wide screening for DNA methylation and histone acetylation (as well as other epigenetic processes) in determining gene expressio”
- Is folic acid good for everyone? (2008, background): “effect that was associated with increased methylation of the CpG site (177, 178).”
- Short- and long-term effects of developmental corticosterone exposure on avian physiology, behavioral phenotype, cognition, and fitness: A review (2011, positive): “…importance to this area of research are more recent findings that variation in maternal care may induce changes in DNA and histone methylation, thus representing an epigenetic effect which can lead to transmission of aspects of parental behavior to future generations (Weaver et al., 2006).”
- Brain plasticity and behaviour in the developing brain. (2011, background): “These changes are correlated with changes in hippocampal cell membrane corticosterone receptors, which in turn are controlled by changes in gene expression (Weaver et al., 2006).”
- Pulling back the curtain on heritability studies: biosocial criminology in the postgenomic era (2014, background): “…early in life (e.g., prenatal factors or child abuse) tend to produce more pronounced epigenetic effects than those that occur later (Bradley et al., 2008; Trembley, 2010), methylation and other epigenetic processes continue throughout the life span (Francis, 2011; Weaver, Meaney, and Szyf, 2006).”
- Child health, developmental plasticity, and epigenetic programming. (2011, background): “They also reported that high maternal care resulted in hypomethylation in some brain regions and hypermethylation in other regions and was reversed by inhibiting histone acetylation (513).”