The Stat family in cytokine signaling.

By J. Ihle. Current Opinion in Cell Biology, 2001

760 citations recorded by the source corpus.

Subfields: Immunology, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/309e3bd01bfb42f91f0ab1d69bbb6202d18654cb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. A. Chawla
2. R. Kastelein
3. P. Murray
4. J. Odegaard
5. T. Mcclanahan
6. R. Jove
7. Alexander H Sprague
8. R. Khalil

In Oncology

1. R. Buettner
2. R. Jove
3. P. Murray
4. Alexander H Sprague
5. R. Khalil

In Pathology and Forensic Medicine

1. R. Jove
2. Alexander H Sprague
3. R. Khalil
4. R. Kastelein

Citations in the corpus

• Inflammatory Cytokines in Vascular Dysfunction and Vascular Disease (2009, background): “Each STAT family member plays a critical role in the biological functions of specific cytokines [15].”
• The STATs of cancer — new molecular targets come of age (2004, neutral): “cgi?&ID=3716&ID=3717&ID=3718">Janus kinase (JAK) family”
• WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27 (2004, background): “Tyrosine phosphorylation of STATs is a requirement for nuclear translocation and transcriptional activity (15).”
• Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. (2002, background): “Because many different cytokines are known to activate STATs (20), it is not surprising that constitutive activation of”
• STAT proteins: From normal control of cellular events to tumorigenesis (2003, background): “The human STATs genes have been identified in three chromosomal clusters: STAT 1 and STAT 4 map on chromosome 2, STAT 2 and STAT 6 on chromosome 12, and STAT 3 and STAT 5a and 5b on chromosome 17 (Ihle, 2001).”
• Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. (2006, background): “…regulates oxidative metabolism in macrophages Although IL-4 exerts a majority of its immunological effects on macrophages via STAT6 proteins (Ihle, 2001;Takeda and Akira, 2000;Wurster et al., 2000), the role of this transcription factor in orchestrating the macrophage metabolic response has…”