A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

By T. Bouwmeester, Angela Bauch, H. Ruffner, P. Angrand, G. Bergamini, K. Croughton, Cristina Cruciat, D. Eberhard, J. Gagneur, S. Ghidelli and 18 more. Nature Cell Biology, 2004

710 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology

View Paper: https://www.semanticscholar.org/paper/309c2956be3015e78bd5f0a68bde6db2edbc1f69

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Sebastian M. B. Nijman
2. A. Dirac
3. T. Brummelkamp
4. René Bernards
5. J. Bradley
6. Weimin He
7. J. Kurreck

In Immunology

1. René Bernards
2. Sebastian M. B. Nijman
3. J. Bradley
4. A. Dirac
5. T. Brummelkamp
6. Weimin He

Citations in the corpus

• A genomic and functional inventory of deubiquitinating enzymes. (2005, background): “Similarly, USP11 and USP9 interact with the NF-κB transcription factors RelB and p100, respectively (Bouwmeester et al., 2004).”
• Regulation of Notch signalling by non-visual β-arrestin (2005, methodology): “LC-MS/MS analysis and peptide identification were performed as described previousl”
• A Census of Human Soluble Protein Complexes (2012, neutral): “…the composition of stably associated human proteins in experiments ranging from dozens to hundreds of different ‘‘baits’’ (Behrends et al., 2010; Bouwmeester et al., 2004; Ewing et al., 2007; Hutchins et al., 2010; Jeronimo et al., 2007; Mak et al., 2010; Sardiu et al., 2008; Sowa et al.,…”
• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation (2015, neutral): “HEK293 cells stably expressing N-terminal FLAG-tagged PAD1, PAD2, PAD3 or PAD4 were engineered by retroviral transduction as described 34 .”
• TNF‐mediated inflammatory disease (2008, background): “transduction, but large-scale physical mapping in combination with loss of function analysis using RNA interference recently identified 221 molecular associations and 80 previously unknown interactors involved in modulation of the TNF–NF-κB pathway alone [9].”