Reply — reconsolidation: The labile nature of consolidation theory

By Karim Nader, G. Schafe, Joseph E LeDoux. Nature Reviews Neuroscience, 2000

629 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/302ed2e0be26b84b7f4d4b77f90b282c69efdf33

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness (2012, background): “The new memory trace involves re-consolidated associations of particular contextual stimuli and its previous associations with new stimuli and behavior (Nader et al., 2000; Quirk and Mueller, 2008).”
Contextual Fear Memories Formed in the Absence of the Dorsal Hippocampus Decay Across Time (2012, background): “, 2002), which provides a mechanism for the transition from active short-term memory to passive long-term memory in a process that occurs for several hours after the acquisition or retrieval of information (Schafe et al., 1999; Nader et al., 2000).”
Memory Reconsolidation and Extinction Have Distinct Temporal and Biochemical Signatures (2004, methodology): “…before or immediately after retrieval of a fear memory disrupts the subsequent expression of that memory, suggesting that retrieval triggers a wave of protein synthesis required for the reconsolidation of memory (Nader et al., 2000a; Taubenfeld et al., 2001; Debiec et al., 2002; Kida et al., 2002).”
Rhythms of the brain (2006, background): “The memory trace may be rekindled by rehearsal, recall, associations, or dreaming (Squire, 1992; Squire and Zola, 1998; McGaugh, 2000; Nader et al., 2000; Sara, 2000; Dudai and Eisenberg, 2004) and strengthened repeatedly.”
Transcription Factors in Long-Term Memory and Synaptic Plasticity (2009, positive): “Because similar interferences can affect the stability of memory after initial learning and recall, the process that transforms a reactivated memory from a labile to a stable form is called reconsolidation (12, 61, 180, 213).”
Synaptic Consolidation: From Synapses to Behavioral Modeling (2015, background): “Synaptic strength changes induced by Hebbian protocols deteriorate over a few hours (early LTP or e-LTP) unless they are consolidated (Dudai and Morris, 2000; Nader et al., 2000).”
Memory Engram Cells Have Come of Age. (2015, positive): “Memory is constructive in nature and the act of recalling a memory renders it labile and highly susceptible to modification (Bartlett, 1932; Nader et al., 2000).”
The hippocampus and related neocortical structures in memory transformation. (2018, background): “…considerable evidence has shown that once a consolidated memory is reactivated, it can become labile and once again become susceptible to the e ﬀ ects of hippocampal disruption, unless it completes a process of ‘ reconsolidation ’ whereupon the memory is restabilized and strengthened [24,88 – 90].”