Pathogenicity islands and the evolution of microbes.

By J. Hacker, J. Kaper. Annual Review of Microbiology, 2000

1,366 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Biomaterials

View Paper: https://www.semanticscholar.org/paper/2f83d9202e0d6746bb14646900b2ef1917fbb4d3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Animal Science and Zoology

1. I. Zilber-Rosenberg
2. Eugene Rosenberg
3. Eugene V. Koonin

In Biomaterials

1. I. Zilber-Rosenberg
2. Eugene Rosenberg

Citations in the corpus

• Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths (2009, background): “coli has been abundantly described [62,63], our data shows that these events take place systematically at the same regions in different genomes.”
• The Enterococcal Surface Protein, Esp, Is Involved in Enterococcus faecalis Biofilm Formation (2001, background): “It is known that adhesins, which mediate the capacity of bacteria to attach to specific eukaryotic receptor molecules, are major virulence factors encoded by PAIs (18).”
• The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “PAI are intrinsically unstable and delete with frequencies that are higher than the normal rate of mutation.”
• Interpolated variable order motifs for identification of horizontally acquired DNA: revisiting the Salmonella pathogenicity islands (2006, background): “Other genomic elements with some of the signatures of GIs include bacteriophages, plasmids, extracellular polysaccharide biosynthesis loci (Hacker and Kaper, 2000; Zhang et al ., 1997) and other gene clusters under specific constraints; these may or may not be recently horizontally acquired.”
• IslandViewer: an integrated interface for computational identification and visualization of genomic islands (2009, background): “…that contain multiple genes of probable horizontal origin, termed genomic islands (GIs), are of significant medical interest because they disproportionately contain genes involved in virulence, antibiotic resistance or other important adaptations (Dobrindt et al ., 2004; Hacker and Kaper, 2000).”
• Ecological fitness, genomic islands and bacterial pathogenicity (2001, background): “Sequencing of several entire genomes revealed that PAIs are much more widespread than previously thought, and represent a paradigm of more general genetic entities that are present in the genomes of many bacterial species and are termed genomic islands (Strauss and Falkow, 1997; Hacker and Kaper, 20”
• CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea (2010, background): “Also, pathogenicity islands are flanked by transposable elements and therefore can transfer between different species by 'hitch-hiking' on conjugative plasmids and temperate phage”
• Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models (2006, background): “If we consider the gene g as not alien (see [2,8]).”
• Sex and virulence in Escherichia coli: an evolutionary perspective (2006, background): “coli maintain low frequencies of homologous recombination, but can occasionally acquire novel genes that result in virulence by horizontal genetic exchange (HGT) (Hacker and Kaper, 2000).”
• Theoretical and practical advances in genome halving (2004, neutral): “York, NY 10029 and 2 Lewis-Sigler Institute for Molecular Biology, Princeton University, Princeton, can thoroughly characterize the binding sites of transcription identification of specific binding motifs much easier, and uncovering previously uncharacterized variation (Johnson et al. , ; Wederell et ”
• The population genetics of commensal Escherichia coli (2010, background): “Therefore, the plasticity of the genome may illustrate the diversity of adaptive paths present in the species: some clusters of genes or genomic islands (including pathogenic island”
• Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis (2008, neutral): “pathogenicity islands in different UPEC strains (125).”
• Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world (2008, background): “Pathogenicity islands are large genomic regions, up to 100 kb in length, and they are typically located near tRNA genes and contain multiple prophages, suggesting that the insertion of these islands is mediated by bacteriophages (165).”
• Pathogenicity Islands in Bacterial Pathogenesis (2004, background): “coli groups and also in other bacterial species (129).”
• Genomic islands: tools of bacterial horizontal gene transfer and evolution (2008, background): “Discrete DNA regions detected by comparative genome sequencing with sizes smaller than 10 kb have been named genomic islets (Hacker & Kaper, 2000).”