Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
By Aurélien Trompette, E. Gollwitzer, K. Yadava, A. Sichelstiel, N. Sprenger, C. Ngom-Bru, C. Blanchard, T. Junt, L. Nicod, N. Harris and 1 more. Nature Medicine, 2014
2,604 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/2ea205ec5ca1ce74bb82096f12bc6a0dfa174f3d
How researchers see this paper
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In Immunology
- O. Harrison
- Y. Belkaid
- P. Kovatcheva-Datchary
- B. B. Finlay
- David S. Wishart
- C. Mackay
- Eric G. Pamer
- F. Bäckhed
In Molecular Biology
- Justin L. Sonnenburg
- E. Sonnenburg
- F. Bäckhed
- Jeroen Raes
- Y. Belkaid
- Eric G. Pamer
- M. Conlon
- A. Bird
In Physiology
- F. Bäckhed
- Jeroen Raes
- Justin L. Sonnenburg
- E. Sonnenburg
- P. Kovatcheva-Datchary
- M. Conlon
- A. Bird
- Curtis Huttenhower
Citations in the corpus
- Butyrate: A Double-Edged Sword for Health? (2018, background): “…increased Tregs and dendritic cell precursors, hematopoiesis of dendritic cells from bone marrow De Vadder et al., 2014 (36); Nøhr et al., 2013 (42); Trompette et al., 2014 (38); Kimura et al., 2011 (39) GPR43/FFAR2 Formate, acetate, propionate, butyrate, and pentanoate Adipocytes, skeletal…”
- Short-chain fatty acids: linking diet, the microbiome and immunity (2024, positive): “Increased circulating levels of propionate resulting from a high-fibre diet in mice were shown to generate anti-inflammatory DCs that seed the lung to limit allergic T H 2 cell responses 148 .”
- Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism (2020, background): “For example, C3 causes protective effects on allergic airway inflammation through FFAR3 [59].”
- Short chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway (2014, background): “Moreover, SCFAs can affect other organs, such as lungs and regulate allergic hypersensitivity.(48) More studies are required to precisely determine the functions of SCFAs in the regulation of the immune system and inflammatory diseases.”
- Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. (2015, positive): “, from fiber-rich diets, and have been shown to ameliorate disease in models of IBD and allergic asthma (Smith et al., 2013; Trompette et al., 2014).”