Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

By A. Haghikia, Stefanie Jörg, Alexander Duscha, Johannes Berg, A. Manzel, A. Waschbisch, Anna Hammer, De-hyung Lee, C. May, N. Wilck and 12 more. Immunity, 2015

617 citations recorded by the source corpus.

Subfields: Immunology, Surgery

View Paper: https://www.semanticscholar.org/paper/caf7fe00ebf43d42bff99639dd0f488702493788

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In Immunology

1. Helen Y Wang
2. Changsheng Xing
3. Rong‐Fu Wang
4. Eran Elinav

Citations in the corpus

• Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases (2019, background): “However, detection of extra intestinal levels implies that these metabolites have systemic functions, as established for central nervous system autoimmunity (46).”
• Salt-responsive gut commensal modulates TH17 axis and disease (2017, neutral): “We analyzed small intestinal lamina propria (siLPL) CD4 + lymphocytes producing IL-17A by flow cytometry at the maximum of intestinal T H 17 expansion on day 3 post MOG immunization (p.i.)25.”
• Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis (2019, background): “tion [72] and in preclinical model of MS as well [73].”
• The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020, background): “One of the best-documented effects of SCFAs is on the immune system since butyrate is capable of inducing Treg differentiation and controlling inflammation (17, 23, 24, 87).”
• Interaction between microbiota and immunity in health and disease (2020, background): “Dietary long-chain fatty acids may exacerbate autoimmunity in the central nervous system (CNS) by modulating the gut microbiome and metabolome.(139) In mice, intake of dietary carbohydrates,(105) certain probiotics,(140) artificial sweeteners(141) and emulsifiers(142) can modulate host immunity and ”