Error-prone repair DNA polymerases in prokaryotes and eukaryotes.

By Myron F. Goodman. Annual Review of Biochemistry, 2002

729 citations recorded by the source corpus.

Subfields: Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/2e41144b08ed6b467d246d84b1566933e442ffc8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Radi Tegova
2. P. Pham
3. R. Bransteitter
4. E. Friedberg
5. A. Britt
6. S. Saumaa
7. J. Petruska
8. Giovanni Maga

In Pathology and Forensic Medicine

1. E. Friedberg
2. A. Britt
3. Radi Tegova
4. S. Saumaa
5. P. Pham
6. R. Bransteitter
7. J. Petruska
8. Giovanni Maga

Citations in the corpus

• Repair of DNA Damage Induced by Solar UV (2004, background): “…they will proceed into a secondary ‘damage tolerance’ phase in which stalled DNA polymerases will be rolled back or removed from sites of damage, and a second set of less fastidious polymerases upregulated to perform ‘dimer bypass,’ the polymerization of DNA past a damaged site (Goodman 2002).”
• The role of specialized DNA polymerases in mutagenesis in Pseudomonas putida (2009, background): “14 for specialized DNA polymerases is enhanced by the induction of expression of these particular DNA polymerases as a response to DNA damage known as SOS-response (Hanaoka, 2001; Goodman, 2002).”
• Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation (2003, methodology): “Absent from our analysis are specific roles for error-prone polymerase”
• Proliferating cell nuclear antigen (PCNA): a dancer with many partners (2003, background): “An alternative pathway for DNA damage tolerance in eukaryotic cells is translesion synthesis (TLS), which relies on specialised polymerases able to carry on DNA synthesis on a damaged template (Goodman, 2002; Hubscher et al., 2002).”
• Loss of DNA Polymerase ζ Causes Chromosomal Instability in Mammalian Cells (2006, background): “For the Rev3L null cells, only one aberration identified in the first series [der(2)t(1;2)] was found in the second group, indicating that the chromosomal instability is a continuous process occurring cell by cell and dispersed throughout the mouse genome.”
• DNA damage and repair (2003, background): “One such damage-tolerance mechanism, called translesion DNA synthesis, involves the replication machinery bypassing sites of base damage, allowing normal DNA replication and gene expression to proceed downstream of the (unrepaired) damag”
• The role of DNA mismatch repair and oxidative DNA damage defense systems in avoidance of stationary phase mutations in Pseudomonas putida (2007, background): “5) 3 69 47 (68) 4 (6) 4 (6) 0 2 (3) 12 (17) 4 62 30 (48) 10 (16) 2 (3) 5 (8) 3 (5) 12 (20) 5 70 30 (43) 9 (13) 3 (4) 6 (9) 0 22 (31) 6 60 18 (30) 12 (20) 0 13 (22) 1 (2) 16 (26) 7 61 16 (26) 11 (18) 0 12 (20) 5 (8) 17 (28)”