Barrier properties of mucus.
By R. Cone. Advanced Drug Delivery Reviews, 2009
1,356 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology, Pharmaceutical Science
View Paper: https://www.semanticscholar.org/paper/2c8b5149c98a44ec7299fc4947481b1d47ce68bc
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Citations in the corpus
- Bacteriophage adhering to mucus provide a non–host-derived immunity (2013, background): “The amino acid backbone of these proteins incorporates tandem repeats of exposed hydrophobic regions alternating with blocks bearing extensive O-linked glycosylation (17).”
- Micro- and macrorheology of mucus (2009, neutral): “However, nanoparticles must efficiently overcome the mucus barrier to avoid rapid clearance [73,74].”
- PEGylation as a strategy for improving nanoparticle-based drug and gene delivery (2015, positive): “However, the viscoelastic and rapidly cleared mucus layers coating the cervicovaginal tract pose a barrier to NP-based drug and gene delivery [122-124].”
- Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues (2008, background): “5–40 MDa in size [15,16] formed by the linking of numerous mucin monomers, each about 0.”
- Oral Drug Delivery with Polymeric Nanoparticles: The Gastrointestinal Mucus Barriers (2011, background): “Olmsted and coworkers determined that many viruses are capable of penetrating mucus [102], by (i) being small enough to avoid being blocked sterically by the mucin mesh, (ii) possessing surfaces without mucoadhesive hydrophobic areas, and (iii) densely coating exposed surfaces with negative and posi”
- Biological and Ecological Roles of External Fish Mucus: A Review (2018, background): “Mucus viscoelasticity determines its ability to block many types of motile bacteria [20], and several studies showed that fish tend to increase their mucus secretion and change their composition when exposed to pathogens [21–23], which may contribute to the defence against these pathogens.”
- Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals (2019, background): “This leads to a very short residence time for the attached agents to reach the epithelium for absorption (50–270 min) [109,110].”
- An Overview of the Immunological Defenses in Fish Skin (2012, methodology): “Skin mucus has evolved to have robust mechanisms that can trap and immobilize pathogens before they can contact epithelial surfaces, because it is impermeant to most bacteria and many pathogens [82].”