Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo

By B. Lendvai, E. Stern, B. Chen, Karel Svoboda. Nature, 2000

844 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/2950f314de3d32f1a6200fe5620193d35d8fc0fc

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Removing brakes on adult brain plasticity: from molecular to behavioral interventions (2010, background): “Likewise in barrel cortex, a brief sensitive period for whisker receptive field tuning emerges concurrent with an increase in experience-dependent spine motility (Lendvai et al., 2000; Stern et al., 2001).”
Stability of dendritic spines and synaptic contacts is controlled by αN-catenin (2004, background): “Even after the establishment of these contacts, the spines are still motile, dynamically changing their shap”
Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus (2006, background): “Studies in visual and somatosensory cortices have shown that spine motility is downregulated by blocking visual and somatosensory input during the peak of synaptogenesis (Lendvai et al., 2000; Konur and Yuste, 2004) and is upregulated during the critical period of monocular deprivation (Majewska and”
Spine Plasticity in the Motor Cortex (2010, background): “During early postnatal stages, spines of cortical neurons are highly plastic, changing length and appearing/disappearing within tens of minutes [29,30].”
Axon pruning: an essential step underlying the developmental plasticity of neuronal connections (2006, background): “…GFP-or yellow fluorescent protein (YFP)-expressing mice have reported that a majority of plastic changes in the adult brain are regressive in nature and the kinetics are much slower than the comparable cases seen in early development (Lendvai et al. 2000; Trachtenberg et al. 2002; Zuo et al. 2005).”
Dissecting tumour pathophysiology using intravital microscopy (2002, background): “Multi-photon laser-scanning microscopy can image structures up to 700 μm deep, depending on the tissues and probes use”
Morphological changes in dendritic spines associated with long-term synaptic plasticity. (2001, background): “This motility had been proposed by Blomberg et al (1977) and Crick (1982) and has now been documented in dissociated cultures (Fischer et al 1998), in brain slices (Dunaevsky et al 1999), and in vivo (Lendvai et al 2000).”
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning (2011, background): “Training induces rapid alterations in synapse morphology and dendritic spine numbers (Lendvai et al., 2000; Holtmaat et al., 2005; Lippman and Dunaevsky, 2005), axonal and dendritic branch remodelling (De Paola et al., 2006), neurogenesis (Christie and Cameron, 2006; Kee et al., 2007), and…”