Stability of dendritic spines and synaptic contacts is controlled by αN-catenin

By K. Abe, O. Chisaka, F. Roy, M. Takeichi. Nature Neuroscience, 2004

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α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly (2005, unknown): “It is interesting to note, in this context, that decreased levels of α-catenin result in increased membrane activity in hippocampal neurons, while overexpression of α-catenin suppress membrane activity (Abe et al., 2004), indicating that α-catenin directly regulates membrane protrusive activity.”
Balancing structure and function at hippocampal dendritic spines. (2008, background): “Once filopodia become spines, telencephalin relocates to the dendritic shaft and is replaced with adhesion molecules, N-cadherin and αcatenin , which stabilize the new spine (Bozdagi et al. 2000, Togashi et al. 2002, Abe et al. 2004).”
α-Catenin as a tension transducer that induces adherens junction development (2010, background): “A vector expressing full-length mouse αE-catenin with a Flag tag at its C terminus (pCA-αE-catenin–Fla”
Adherens junction: molecular architecture and regulation. (2009, background): “Removal of neural a-catenin (aN-catenin) from synaptic AJs destabilizes synaptic contacts (Abe et al. 2004).”