The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

By Kelley S. Yan, Luis A. Chia, Xingnan Li, A. Ootani, James Su, Josephine Y. Lee, N. Su, Yuling Luo, S. Heilshorn, M. Amieva and 3 more. Proceedings of the National Academy of Sciences of the United States of America, 2011

828 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/279c10dc3795bbb0a97c3342d7be06d17d0f0f44

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Hans Clevers
2. R. Nusse
3. K. Loh
4. Elaine Fuchs
5. C. Blanpain
6. Xi He
7. M. Resh
8. S. Angers

In Oncology

1. R. Nusse
2. Hans Clevers
3. K. Loh
4. Pengfei Lu

In Radiology, Nuclear Medicine and Imaging

1. Hans Clevers

Citations in the corpus

• The intestinal crypt, a prototype stem cell compartment. (2013, background): “A follow-up study proposed a model in which Lgr5 stem cells mediate homeostatic self-renewal, whereas Bmi1+ stem cells mediate injury-induced regeneration (Yan et al., 2012).”
• An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control (2014, background): “Therefore, CBCs constitute multipotent intestinal stem cells (25) that require Wnt for proliferation (27, 33), perhaps explaining why Wnt is crucial for intestinal renewal.”