Directed proteomic analysis of the human nucleolus.

By Jens S. Andersen, Carol E. Lyon, A. Fox, Anthony Kar Lun Leung, Yun Wah Lam, Hanno Steen, Matthias Mann, Angus I. Lamond. Current Biology, 2002

1,027 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/275bdf73c30bef45a0e8fa9411a779718d6263dd

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Citations in the corpus

Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes (2006, neutral): “− and, thence, H 2 O 2 .”
From genomics to proteomics (2003, background): “This point is aptly illustrated by recent proteomic analysis of the yeast and human nucleolus, in which both directed and undirected efforts uncovered a vast network of protein interactions, many of which impinge on the conserved process of ribosome biogenesi”
Comprehensive proteomic analysis of the human spliceosome (2002, background): “Sixth, some of the proteins are known to co-localize with splicing factors in nuclear speckles and/or to localize in the nucleu”
The multifunctional nucleolus (2007, background): “However, the ability to purify nucleoli on a large scale, combined with important advances in the identification and analysis of proteins using mass spectrometry, has now provided a wealth of information regarding the nucleolar proteom”
Global analysis of protein localization in budding yeast (2003, background): “Recently, mass spectrometric analysis of the human nucleolus identified 271 proteins, 166 of which have homologues in yeas”
Ribosome assembly in eukaryotes. (2003, background): “In higher eukaryotes many homologues of known pre-ribosomal factors were found enriched in the nucleolar fraction (Andersen et al., 2002; Scherl et al., 2002) thus confirming that the majority of the assembly steps in ribosome biogenesis are nucleolar.”
COMPARTMENTS: unification and visualization of protein subcellular localization evidence (2014, background): “These databases also integrate data from cDNA tagging projects (6–8), proteomics-based experiments (9, 10) and microscopy-based high-throughput localization studies (11–14).”
Human protein reference database—2006 update (2005, background): “Updated annotations involving subcellular localization include 489 nucleolar proteins (6,7) and 270 secreted proteins (8).”
Analyzing yeast protein–protein interaction data obtained from different sources (2002, background): “The two largest common networks in the intersection comprise nucleolar proteins, including yeast orthologs of novel proteins recently detected in purified human nucleolar preparation”