Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.
By Bruno Dubois, H. Feldman, C. Jacova, Harald Hampel, José Luis Molinuevo, Kaj Blennow, Steven DeKosky, S. Gauthier, D. Selkoe, Randall J. Bateman and 23 more. Lancet Neurology, 2014
3,079 citations recorded by the source corpus.
Subfields: Physiology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/26057af498eb494bd88abb036dee4b13e2f76d9d
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Physiology
- Kaj Blennow
- Henrik Zetterberg
- Oskar Hansson
- Clifford R. Jack Jr.
- Michael D. Geschwind
- Michael G. Erkkinen
- Mee‐Ohk Kim
- Reisa A. Sperling
In Psychiatry and Mental health
- Kaj Blennow
- Henrik Zetterberg
- Oskar Hansson
- Michael D. Geschwind
- Michael G. Erkkinen
- Mee‐Ohk Kim
- Clifford R. Jack Jr.
- Reisa A. Sperling
Citations in the corpus
- Post-stroke cognitive impairment: epidemiology, mechanisms and management. (2014, methodology): “According to international working group (IWG) for new research criteria for the diagnosis of AD, the IWG-2 criteria, besides the existence of clinical and biomarker evidences of AD, the mixed AD with stroke should also include the stroke history, or focal neurological features supported by neuroima”
- Preclinical Alzheimer’s disease: Definition, natural history, and diagnostic criteria (2016, background): “These biomarkers have recently divided into (1) pathophysiological/ diagnostic markers, reflecting AD pathology at any point on the disease continuum and (2) topographical and/or prognostic markers, reflecting “downstream” damage [11].”
- Alzheimer's disease (2018, background): “Both sets of criteria also recognize atypical, nonamnestic presentations [46,48] (Table 1).”
- NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease (2018, positive): “While differences remain, IWG 2016 and the NIA research framework are aligned on the key issue that the combination of an abnormal Ab and tau biomarker constitutes AD regardless of cognitive symptoms, and thus AD is a biologically defined entity throughout its continuum.”
- Automatic speech analysis for the assessment of patients with predementia and Alzheimer's disease (2015, background): “Repeated steps 1 through 5 with different random selections of the test versus training sets 7.”
- The Impact of Age on Cognition (2015, background): “New diagnostic classifications for AD have recently been proposed that incorporate these biomarkers.(35,36) This classification system includes a determination of whether there is evidence of amyloid deposition, neurodegeneration, or both and whether cognition and function are normal or abnormal.”
- Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. (2018, background): “Atypical clinical presentations of AD include variants that reflect dysfunction outside the mesial temporal areas—namely, in the posterior parieto-occipital, frontal, motor, and language areas (Lee et al. 2011; Dubois et al. 2014; Sha and Rabinovici 2016).”