Basal ganglia output and cognition: evidence from anatomical, behavioral, and clinical studies.

By F. Middleton, Peter Strick. Brain and Cognition, 2000

697 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/259d4a9c4bf3906292eecd1a5b62c9160ca5b7a0

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In Cellular and Molecular Neuroscience

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Citations in the corpus

Hold your horses: A dynamic computational role for the subthalamic nucleus in decision making (2006, positive): “…activity in Go cells via D1 receptors, while inhibiting NoGo activity via D2 receptors (Aubert, Ghorayeb, Normand, & Bloch, 2000; Brown et al., 2004; Frank, 2005a; Gerfen, 1992; Hernandez-Lopez, Bargas, Surmeier, Reyes, & Galarraga, 1997; Hernandez-Lopez et al., 2000; Joel & Weiner, 1999).”
Towards an executive without a homunculus: computational models of the prefrontal cortex/basal ganglia system (2007, background): “(iv) Selective updating occurs owing to the existence of independently updatable parallel loops of connectivity through different areas of the BG and frontal cortex (Alexander et al. 1986; Graybiel & Kimura 1995; Middleton & Strick 2000).”
Dynamic Dopamine Modulation in the Basal Ganglia: A Neurocomputational Account of Cognitive Deficits in Medicated and Nonmedicated Parkinsonism (2005, methodology): “…for the two classes of deficits have been (a) that the damaged BG is interconnected in a functional circuit with prefrontal cortex [PFC] (Middleton & Strick, 2000; Alexander, DeLong, & Strick, 1986), thereby producing frontal deficits, and (b) due to damage to a ‘‘neostriatal habit…”
Contributions of memory circuits to language: the declarative/procedural model. (2004, background): “The basal ganglia, in particular the neostriatum, receive input projections from multiple cortical areas, especially in frontal cortex, but also from other structures, including the medial temporal lobe (Alexander & Crutcher, 1990; Middleton & Strick, 2000b; Wise et al., 1996).”
Developmental Stages and Sex Differences of White Matter and Behavioral Development through Adolescence: A Longitudinal Diffusion Tensor Imaging (DTI) Study (2013, positive): “Further, late maturation was also seen in the basal ganglia, which forms loops with the cortex and is a key relay in cognitive and emotional processing (Middleton and Strick, 2000).”
Evidence for Segregated and Integrative Connectivity Patterns in the Human Basal Ganglia (2008, background): “…remote cortical areas and the pallidum for channeling output via thalamic targets (for review, see Haber, 2003; Utter and Basso, 2008), it is clear that the basal ganglia must have a major influence on sensorimotor, limbic, and cognitive information processing (Middleton and Strick, 2000, 2002).”
Subcortical structures and cognition (2009, background): “Multiple, parallel, segregated circuits between the cortex and basal ganglia and between the cortex and cerebellum provide the anatomic substrate for supporting not only motor, but also cognitive and emotional function (Middleton & Strick, 2000).”
Specific language impairment is not specific to language: the procedural deficit hypothesis. (2005, positive): “Indeed, neurodevelopmental as well as neurodegenerative disorders affecting the basal ganglia have been characterized as primarily " hyper " or " hypo " in nature (Bradshaw, 2001; Jankovic and Tolosa, 1993; Middleton and Strick, 2000a, 2000b).”
The ecology of human fear: survival optimization and the nervous system (2015, background): “The degree of affect and the ability to regulate it may determine the amount of cognitive flexibility available (being cool under pressure vs. fighting or fleeing).”
Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. (2006, background): “How can one model the deficit of activation of the PFC targets? Several studies have promoted the concept of a relative segregation of the frontal-basal ganglia loops organized in parallel pathways throughout the basal ganglia (Alexander et al., 1986; Hoover and Strick, 1993; Wichmann and DeLong, 19”
The Declarative/Procedural Model (2020, background): “Likewise, different frontal/basal ganglia circuits subserve different sorts of information (Middleton & Strick, 2000).”