Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). II. Role at Class I and class II CAP-dependent promoters.

By Yuhong Zhou, T. Merkel, R. Ebright. 1994

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Catabolite activator protein: DNA binding and transcription activation. (2004, background): “AR1 of the upstream subunit of CAP (blue in Figure 3b) [34,35,53,54] interacts with the ‘287 determinant’ of aCTD (yellow in Figure 3b) [55].”
Transcription activation by catabolite activator protein (CAP). (1999, background): “Thus, the DNA site for CAP can be centered near position À93, position À83, position À72, or position À62.”
cAMP Receptor Protein from Escherichia coli as a Model of Signal Transduction in Proteins – A Review (2008, background): “CRP-dependent promoters can be divided into three classes, depending on the location of the CRP DNA-binding site and the number of protein molecules involved in the initiation of transcription [Busby and Ebright, 1997, 1999; Ebright, 1993; Zhou et al., 1994].”
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface. (1997, background): “This difference is of importance in that residues 150 to 165 comprise the ‘‘activating region’’ of CAP, which makes direct protein-protein contact with RNA polymerase in transcriptional activation (Zhou et al., 1993, 1994a,b; Heyduk et al., 1993; Chen et al., 1994).”