Discovery of five conserved β-defensin gene clusters using a computational search strategy

By B. Schutte, J. Mitros, J. Bartlett, Jesse D. Walters, H. Jia, M. Welsh, T. Casavant, P. McCray. Proceedings of the National Academy of Sciences of the United States of America, 2002

524 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/21ad6dc213613d5c1a7edcc5cfd72910abf24e57

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Microbiology

1. A. Ouellette
2. M. Malmsten
3. Mukesh Pasupuleti
4. M. Selsted
5. A. Schmidtchen

In Molecular Biology

1. A. Ouellette
2. M. Malmsten
3. Mukesh Pasupuleti
4. M. Selsted
5. A. Schmidtchen

Citations in the corpus

• Antimicrobial peptides: key components of the innate immune system (2012, background): “In humans, more than 30 α-defensin genes have been predicted using a bioinformatic approach (Schutte et al., 2002), however at the protein level only 6 α-defensins have been reported.”
• Defensins: antimicrobial peptides of innate immunity (2003, unknown): “Four additional defensin clusters have been identifie”
• Mammalian defensins in the antimicrobial immune response (2005, background): “and by bioinformatics approaches that have identified about 30 human β-defensin genes and about 45 β-defensin genes in mic”