Nitrogen regulation in Saccharomyces cerevisiae.

By B. Magasanik, C. Kaiser. Gene, 2002

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Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae (2014, background): “The expression of NCR genes results from the interplay of four transcription factors, two activators, Gln3 and Gat1/Nil1, and two repressors, Gzf3/Nil2/Deh2 and Dal80/Uga3, which bind to GATA sequences in the promoters (Cooper, 2002; Magasanik & Kaiser, 2002).”
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control (2011, background): “Key among these intermediates is a-ketoglutarate, the precursor of glutamate and glutamine from which all nitrogen-containing metabolites evolve (Magasanik and Kaiser 2002).”
Nutritional Control of Growth and Development in Yeast (2012, background): “…suggested that the quantity and quality of nitrogen source is perceived as the level of intracellular glutamine: mutations in GLN1 that result in a partially active glutamine synthetase elicit transcriptional patterns similar to those obtained by inhibition of TORC1 (Magasanik and Kaiser 2002).”
Free Amino Nitrogen in Brewing (2019, background): “Magasanik and Kaiser (2002) have summarised nitrogen metabolism in S. cerevisiae as the result of three distinct elements: i.”