Toxicity and tissue distribution of magnetic nanoparticles in mice.

By Jun Sung Kim, Tae-Jong Yoon, K. Yu, B. Kim, Sung Jin Park, Hyun Woo Kim, K. Lee, Seung Bum Park, Jinkyu Lee, M. Cho. Toxicological Sciences, 2006

603 citations recorded by the source corpus.

Subfields: Biomaterials, Health, Toxicology and Mutagenesis, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/204f8dfee7da09a1c5bce687d42e9f6eac19db05

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In Biomaterials

In Health, Toxicology and Mutagenesis

In Materials Chemistry

Citations in the corpus

Nanotoxicity of iron oxide nanoparticle internalization in growing neurons. (2007, background): “While historically Fe2O3 nanoparticles are considered to be well tolerated in vivo [19,20], the effects of moderate to high intracellular concentrations of Fe2O3 nanostructures upon cell function remain to be adequately elucidated.”
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers. (2009, methodology): “2 mg/mL mitomycin C used as positive control led to a drastic increase [41].”
Nanoparticle therapeutics: an emerging treatment modality for cancer (2008, background): “The careful analysis of toxicities of nanostructures in animal models revealed no detrimental effects for some (for example, silica coated magnetic 50 nm particle”
Magnetic nanoparticles for theragnostics (2009, background): “The time-course of nanotoxicity measures may help reconcile studies demonstrating safety of MNPs [27,56,119] with those of transient and acute in vivo toxicity [119,124].”
The nanosilica hazard: another variable entity (2010, background): “The ability of silica-coated nanomaterials to penetrate the bloodbrain barrier also strongly suggests that extensive studies are required to clarify the potential chronic toxicity of these materials [14].”
Nanomaterials in the environment: Behavior, fate, bioavailability, and effects (2008, background): “Nanoparticles can enter cells by diffusing through cell membranes [71] as well as through endocytosis [72] and adhesion”
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION) (2010, background): “Mechanisms associated with toxicity SPION have attracted much attention not only because of their superparamagnetic properties but also because they have been shown to be associated with low toxicity in the human body (12, 13, 39, 40).”
Biogenic synthesis of nanoparticles: A review (2015, positive): “NP interactions are reported to be size dependent (Kim et al., 2006).”