Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.

By R. Landsiedel, M. D. Kapp, Markus Schulz, K. Wiench, Franz Oesch. Mutation research, 2009

369 citations recorded by the source corpus.

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Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay (2014, background): “For these reasons nanotoxicology and nanogenotoxicology are expanding as novel fields that are looking for the potential risk of nanomaterials as well as their possible mechanisms of action (Landsiedel et al., 2009; Singh et al., 2009; Ai et al., 2011).”
In vitro approaches to assess the hazard of nanomaterials (2017, background): “zinc oxide, titanium dioxide, magnetic NPs) were negative (Landsiedel et al., 2009).”
NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. (2009, background): “Two recent reviews have also addressed this issue and have made recommendations focused around ensuring adequate materials characterisation, use of standardised experimental methods and assessment of the correlation between in vitro and in vivo results [192,193].”