Circulating microparticles: pathophysiology and clinical implications.

By A. Piccin, W. Murphy, O. Smith. Blood reviews, 2007

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Tetraspanins in Extracellular Vesicle Formation and Function (2014, background): “asymmetry leading to phosphatidylserine exposition, which in turn leads to modifications in membrane-cytoskeleton contacts, followed by membrane curvature, and vesicle scission (78).”
Microvesicles: mediators of extracellular communication during cancer progression (2010, background): “Growing evidence demonstrating their bona fide presence in body fluids, such as blood, urine and ascites (Graves et al., 2004; Piccin et al., 2007; Smalley et al., 2008; Taylor and Gercel-Taylor, 2008), and their potential to serve as indicators in the diagnosis, prognosis and surveillance of a vari”
Exosomes: extracellular organelles important in intercellular communication. (2010, background): “Regulation of this process involves several enzymes such as calpain, flippase, floppase, scramblase and gelsolin [15].”
Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life (2012, background): “While microbial SMV release may be controlled via mechanisms used in mammalian SMV release (via various enzymes, including calpain, flippase, floppase, scramblase, and gelsolin [68]), this process is currently uncharacterized.”