MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

By L. Michel, Vasco Liberal, Anupam Chatterjee, Regina Kirchwegger, B. Pasche, W. Gerald, Max Dobles, Peter K. Sorger, V. Murty, R. Benezra. Nature, 2001

801 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/1e0dc77c21a1bab0f6222a92f1bc48e24beadf67

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Hongtao Yu
2. Xuelian Luo

In Molecular Biology

1. Scott W. Lowe
2. Hongtao Yu
3. R. Benezra
4. Xuelian Luo
5. J. Massagué
6. J. Campisi

In Oncology

1. Scott W. Lowe
2. J. Campisi
3. Jesús Gil

Citations in the corpus

• Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. (2007, positive): “As anticipated from such a model, partial loss of Mad2 function by genetic manipulation leads to premature degradation of Securin and separation of the sister chromatids (Michel et al., 2001).”
• Protein Metamorphosis: The Two-State Behavior of Mad2 (2008, background): “N IH -PA Author M anuscript N IH -PA Author M anuscript 2004; Jeganathan et al., 2007; Michel et al., 2001; Weaver et al., 2007).”