Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.
By Vivian S. W. Li, S. Ng, P. Boersema, T. Low, W. Karthaus, Jan. P. Gerlach, S. Mohammed, Albert J. R. Heck, M. Maurice, T. Mahmoudi and 1 more. Cell, 2012
912 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/1d82c988beb30e5111c5211e93b8e823b2414e9f
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In Molecular Biology
Citations in the corpus
- YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response. (2014, background): “See also Figure S3. leagues (Li et al., 2012) that reported similar observations.”
- Wnt/ b -Catenin Signaling, Disease, and Emerging Therapeutic Modalities (2017, background): “As a consequence, the complex becomes saturated by the phosphorylated form of b-catenin, leading to accumulation of newly synthesized b-catenin, free to translocate to the nucleus and to activate target genes (Li et al., 2012; Azzolin et al., 2014).”