Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

By T. Reyes, K. Lewis, M. Perrin, K. Kunitake, J. Vaughan, C. Arias, John B. Hogenesch, J. Gulyás, J. Rivier, W. Vale and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2001

915 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Social Psychology

View Paper: https://www.semanticscholar.org/paper/1c4c19af04591bba70c2d0c82e42ff1ee49566f9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. W. Vale
2. Sean M Smith
3. S. Maier
4. Abigail Zisk A.B.
5. M. D. De Bellis
6. G. Koob

In Biological Psychiatry

1. W. Vale
2. Sean M Smith
3. G. Koob

In Social Psychology

1. W. Vale
2. Sean M Smith
3. S. Maier
4. Linda R. Watkins
5. Abigail Zisk A.B.
6. M. D. De Bellis

Citations in the corpus

• Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor (2001, background): “As shown by aligning the mature regions of related CRH family hormones, the putative human SCP and two pufferfish orthologs share greater sequence identity (72% between human SCP and Takifugu SCP) compared with human SRP, a newly reported mouse urocortin II (ref”
• The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress (2006, background): “In the mammalian brain, Ucn 1 is predominantly expressed in the Edinger-Westphal nucleus(24) and Ucn 2 expression is restricted to the PVN and locus coeruleus.(25) Ucn 3 has a wider distribution in the brain and is localized in the perifornical area of the hypothalamus, BNST, lateral septum (LS), an”
• A role for brain stress systems in addiction. (2008, neutral): “The type 2 urocortins, urocortin 2 (Reyes et al., 2001) and urocortin 3 (Lewis et al.”
• Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. (2005, background): “In addition, CRH is relatively selective for CRHR1, with high dosages being required to activate CRHR2 (Reyes et al., 2001).”