A Downstream Mediator in the Growth Repression Limb of the Jasmonate Pathway[W][OA]

By Yuanxin Yan, Stéphanie Stolz, Aurore Chételat, P. Reymond, M. Pagni, L. Dubugnon, Edward E. Farmer. The Plant Cell Online, 2007

688 citations recorded by the source corpus.

Wounding plant tissues initiates large-scale changes in transcription coupled to growth arrest, allowing resource diversion for defense. These processes are mediated in large part by the potent lipid regulator jasmonic acid (JA). Genes selected from a list of wound-inducible transcripts regulated by the jasmonate pathway were overexpressed in Arabidopsis thaliana, and the transgenic plants were then assayed for sensitivity to methyl jasmonate (MeJA). When grown in the presence of MeJA, the roots of plants overexpressing a gene of unknown function were longer than those of wild-type plants. When transcript levels for this gene, which we named JASMONATE-ASSOCIATED1 (JAS1), were reduced by RNA interference, the plants showed increased sensitivity to MeJA and growth was inhibited. These gain- and loss-of-function assays suggest that this gene acts as a repressor of JA-inhibited growth. An alternative transcript from the gene encoding a second protein isoform with a longer C terminus failed to repress jasmonate sensitivity. This identified a conserved C-terminal sequence in JAS1 and related genes, all of which also contain Zim motifs and many of which are jasmonate-regulated. Both forms of JAS1 were found to localize to the nucleus in transient expression assays. Physiological tests of growth responses after wounding were consistent with the fact that JAS1 is a repressor of JA-regulated growth retardation.

Subfields: Insect Science, Plant Science

View Paper: https://www.semanticscholar.org/paper/1c4aec57ca5b92ca719ebfb6cda1f1193b1dc89e

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Citations in the corpus

The Arabidopsis CORONATINE INSENSITIVE1 Protein Is a Jasmonate Receptor[C][W] (2009, background): “…COI1 in the JA pathway, forms a SCF complex that recruits substrates for ubiquitination and subsequent degradation by the 26S proteasome to regulate plant responses (Dharmasiri et al., 2005; Kepinski and Leyser, 2005; Chini et al., 2007; Thines et al., 2007; Yan et al., 2007; Katsir et al., 2008).”
Growth-defense tradeoffs in plants: a balancing act to optimize fitness. (2014, neutral): “The JAZ-family proteins repress JA signaling by directly binding to the MYC family of transcription factors required for the expression of JA-responsive genes (Chini et al., 2007; Thines et al., 2007; Yan et al., 2007).”
Glutathione (2011, neutral): “Some GSTs that are induced by jasmonic acid (JA; Yan et al., 2007) or that have been shown to have activity against oxylipins (Mueller et al., 2008) are differentially regulated in response to H2O2 and/ or GR defi ciency (Mhamdi et al., 2010a).”
Plant immunity to insect herbivores. (2008, background): “Second, dominant mutations in the conserved C-terminal domain of JAZ proteins stabilize them against SCFCOI1-mediated degradation and, as a consequence, reduce the plant’s responsiveness to JA/MeJA (19, 129, 143).”
Control of Jasmonate Biosynthesis and Senescence by miR319 Targets (2008, background): “Importantly, several links between JA and cell cycle progression as well as growth have previously been demonstrated (e.g., [78, 79 ]).”
Glutathione in plants: an integrated overview. (2012, positive): “Several GSTs are among early JA-induced genes or may catalyse formation of GS-oxylipin conjugates (Davoine et al. 2006; Yan et al. 2007; Mueller et al. 2008).”
(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate. (2009, background): “thaliana and tomato, and involves the Jas motif in JAZ protein”
Hormone crosstalk in plant disease and defense: more than just jasmonate-salicylate antagonism. (2011, background): “Mutational and transcriptional approaches revealed a family of 12 JASMONATE ZIM-domain-containing ( JAZ) proteins that repress JA signaling (33, 192, 224).”
Poplar and Pathogen Interactions: Insights from Populus Genome-Wide Analyses of Resistance and Defense Gene Families and Gene Expression Profiling (2009, background): “Jasmonate ZIM-domain (JAZ) transcriptional repressors were recently identified as key regulators of jasmonate responses (Chini et al., 2007; Thines et al., 2007; Yan et al., 2007).”
Jasmonate Biosynthesis, Perception and Function in Plant Development and Stress Responses (2013, background): “3 (Yan et al., 2007), which lost a portion of Jas domain, are still fertile.”
The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis thaliana[C][W] (2011, methodology): “Trichome formation is initiated by various environmental cues, such as wounding and insect attack (Larkin et al., 1996; Serna andMartin, 2006; Yoshida et al., 2009), and by different endogenous developmental signals, including phytohormones, such as gibberellin (Perazza et al., 1998) and jasmonate…”
Jasmonates: biosynthesis, metabolism, and signaling by proteins activating and repressing transcription (2016, background): “In 2007, the family of Arabidopsis JAZ proteins were discovered to be the substrates of SCF, and interact with and inhibit the TF MYC2 to repress JA responses (Chini et al., 2007; Thines et al., 2007; Yan et al., 2007).”