An insular view of anxiety.

By Martin P. Paulus, Murray B. Stein. Biological Psychiatry, 2006

1,314 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/1bf62a279ca4582c9e48ce6a5b36520c4e58a7d9

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In Cognitive Neuroscience

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Citations in the corpus

Social Support and Money as Pain Management Mechanisms (2008, background): “Anticipation of monetary loss leads to activation in the insula (Paulus & Stein, 2006), another region associated with anticipation of pain besides ACC (Rainville, 2002).”
Mental fatigue: costs and benefits. (2008, background): “It has recently been proposed that the insula is involved in the processing of prospective aversive bodily states (Paulus and Stein, 2006), which would account for the role of this structure in both financial loss and punishment and the processing of energetical costs.”
Neurobiology of anorexia and bulimia nervosa. (2008, background): “The insula plays a key role in interoceptivemonitoring of the sensations that are important for the integrity of the internal body state and connecting to systems, through dorsolateral striatal pathways that are important for allocating attention, evaluating context, and planning actions [209,210,21”
Knowing your own heart: distinguishing interoceptive accuracy from interoceptive awareness. (2015, neutral): “It has been suggested that individuals ho are prone to anxiety show an altered interoceptive predicion signal, through which they manifest a heightened discrepancy chology 104 (2015) 65–74 between observed and expected bodily states (Paulus & Stein, 2006, 2010).”
Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response (2010, background): “Paulus and Stein (2006) have put forward a theoretical account of anxiety emphasizing the role of the insula in the generation of feeling states and awareness of bodily sensations.”
Visceral influences on brain and behavior. (2013, neutral): “The size and reactivity of anterior insular regions predicts both interoceptive sensitivity and the potential to experience emotions, particularly anxiety (Critchley et al., 2004; Paulus and Stein, 2006).”
Affective Neuroscience: Past, Present, and Future (2009, background): “Along similar lines, the proposal has been put forward that the insula may provide information about anticipated body states associated with conditioned stimuli (Paulus & Stein, 2006), which can be used to inform attention allocation and action execution.”
Increased amygdala and insula activation during emotion processing in anxiety-prone subjects. (2007, background): “We hope that these observations will lead to more careful scrutiny of insular activity in future studies of psychopathology so that the role of this structure in emotion processing and its functional relationship to other elements of anxiety-related circuitry can be more fully elaborated (72).”
The influence of negative emotions on pain: Behavioral effects and neural mechanisms (2009, neutral): “It has recently been proposed that the anterior insula not only receives interoceptive information but is also able to generate a predictive model (Paulus and Stein, 2006), which provides the individual with a signal of how the body will feel.”
Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making (2008, methodology): “These data support a broader role for the insular cortex in signalling aversive consequences (Paulus and Stein, 2006), potentially via the representation of bodily sensations like unease or dread.”
Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies. (2009, neutral): “This insular subregion provides information about aversive body states associated with conditional stimuli, signalling this information to prefrontal brain areas that are critical for the allocation of attention and the execution of actions.(162) The cognitive control of appraisal and emotional rele”
Regulation of anterior insular cortex activity using real-time fMRI (2007, background): “Recently an interesting hypothesis to explain anxiety proneness has been proposed by Paulus and Stein (2006) indicating the anterior insula as the key region for integration of affective and cognitive processing.”
Resting state functional connectivity in addiction: Lessons learned and a road ahead (2012, result): “Such a view is consistent with previous proposals relating insula dysfunction with other neuropsychiatric disorders such as anxiety (hyperactivity: Paulus and Stein, 2006) and autism spectrum disorders (hypoactivity: Uddin and Menon, 2009).”
Interoception in anxiety and depression (2010, background): “Specifically, consistent with our prior view of the role of insula in anxiety (Paulus and Stein 2006), this neural structure provides the contextualized body prediction error signal to other brain structures.”
An Interoceptive Predictive Coding Model of Conscious Presence (2011, methodology): “Our model therefore extends that of Paulus and Stein (2006): Chronically high anxiety may result from chronically elevated interoceptive prediction error signals, leading to overactivation in AIC as a result of inadequate suppression of these signals.”