Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure.

By W. Welshons, Susan C. Nagel, F. V. vom Saal. Endocrinology, 2006

1,021 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Pollution

View Paper: https://www.semanticscholar.org/paper/1a7f8708a3e5fef35f3e4b2850358ad558cdf780

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Health, Toxicology and Mutagenesis

1. B. Rubin
2. W. Welshons
3. J. Heindel
4. F. V. vom Saal
5. Laura N. Vandenberg
6. J. Rochester
7. S. Swan

In Pollution

1. B. Rubin
2. F. V. vom Saal

Citations in the corpus

• In vivo effects of bisphenol A in laboratory rodent studies. (2007, background): “However, effects of BPA mediated by binding to androen and thyroid hormone receptors appear to require higher oses than those required to elicit estrogenic or antiestrogenic esponses [7].”
• Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention (2019, background): “Why some EDCs produce non-traditional dose-response curves is not understood [216].”
• In vitro molecular mechanisms of bisphenol A action. (2007, neutral): “, that BPA is a SERM [4].”
• Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A (2010, neutral): “It is also found in papers and in implanted medical devices and other medical equipment (Welshons et al. 2006).”
• Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. (2007, background): “While BPA was initially considered to be a “weak” estrogen based on a lower affinity for estrogen receptor alpha relative to estradiol [18], research shows that BPA is equipotent with estradiol in its ability activate responses via recently discovered estrogen receptors associated with the cell memb”
• Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. (2012, background): “BPA also produces significant effects in the adult, with some of the effects being mediated by the ER (57) and others by ER (58).”
• Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. (2012, neutral): “In the multitude of chemicals that have never been tested at low doses, or in the development of new chemicals, to determine whether a chemical has low-dose effects in laboratory animals, we suggest setting the NOAEL or LOAEL from traditional toxicological studies as the highest dose in experiments ”
• Human exposure to bisphenol A (BPA). (2007, background): “[6] Welshons WV, Nagel SC, vom Saal FS.”