Regulation of stearoyl-CoA desaturases and role in metabolism.

By J. Ntambi, M. Miyazaki. Progress in lipid research, 2004

724 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/19ffed11390fd4fffa1591a93ca3d3bbe0b91e18

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. G. Hotamışlıgil
2. Haiming Cao
3. Nikos Koundouros
4. G. Poulogiannis

In Molecular Biology

1. Jessica Rios-Esteves
2. M. Resh
3. Haiming Cao
4. Nikos Koundouros
5. G. Poulogiannis
6. G. Hotamışlıgil

In Surgery

1. Haiming Cao
2. Jessica Rios-Esteves
3. M. Resh
4. G. Hotamışlıgil
5. C. Hetz

Citations in the corpus

• Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism (2008, positive): “Hepatic SCD-1 expression is regulated by a variety of hormones and nutritional factors including insulin and polyunsaturated fatty acids (PUFAs) ( Ntambi and Miyazaki, 2004 ) via transcription factor-binding elements located 1.5 kb upstream of the SCD-1 transcription initiation site (Chu et al., 200”
• Reprogramming of fatty acid metabolism in cancer (2019, background): “2).(26,36,37) The regulation of de novo lipogenesis occurs largely at the transcriptional level through the activation of sterol regulatory element-binding proteins (SREBPs), of which three main transcription factors exist: SREBP1a and SREBP1c arising from the alternative splicing of SREBPF1, and SR”
• Factors affecting odd- and branched-chain fatty acids in milk: A review (2006, background): “…C17:1 (Vlaeminck et al., unpublished) suggests an increase in mammary 9-desaturase activity, which could be induced by higher blood glucose levels (Ntambi and Miyazaki, 2004) due to higher ruminal propionate proportions (Fitzgerald and Murphy, 1999; Vlaeminck et al., 2004b) or higher duodenal…”
• Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. (2008, background): “Although not yet demonstrated, it could be speculated that like alcohol and insulin [237], cigarette smoking up-regulates SCD resulting in higher amounts of 16:1 n 7 and 18:1 n 9 in blood lipids.”
• Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins (2013, background): “It introduces a cis-double bond at position 9 of palmitoyl-CoA (16:0) and stearoyl-CoA (18:0) to generate palmitoleoylCoA (16:1) and oleoyl-CoA (18:1), respectively (Miyazaki et al., 2006; Ntambi and Miyazaki, 2004).”