HIV-1 genome nuclear import is mediated by a central DNA flap.
By Véronique Zennou, C. Petit, D. Guétard, Ulf Nerhbass, L. Montagnier, P. Charneau. Cell, 2000
895 citations recorded by the source corpus.
Subfields: Infectious Diseases, Molecular Biology, Virology
View Paper: https://www.semanticscholar.org/paper/19a127e9289198a67e79bde16368be2885eaed5f
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In Molecular Biology
Citations in the corpus
- A quantitative assay for HIV DNA integration in vivo (2001, methodology): “These genomes were packaged with HIV proteins and the vesicular stomatitis virus G (VSV-G) protein envelope, allowing efficient infection of diverse cell type”
- Gene therapy: trials and tribulations (2000, background): “Extra features that have improved vectors include the central polypurine tract (cPPT), which allows internal initiation of second-strand DNA synthesis and probably aids in the transport of the pre-integration complex to the nucleu”