Adiponectin – journey from an adipocyte secretory protein to biomarker of the metabolic syndrome

By M. Trujillo, Philipp E. Scherer. Journal of Internal Medicine, 2005

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The Hormonal Control of Food Intake (2007, positive): “Other Signals from Adipocytes Adiponectin Adiponectin is an adipocyte-derived hormone that has been proposed to play an important role in energy homeostasis (Trujillo and Scherer, 2005).”
Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans (2007, background): “In contrast, visceral fat might have beneficial metabolic effects by producing adiponectin (11), which increases insulin sensitivity and decreases glucose intolerance and diabetes (12).”
Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training (2013, neutral): “Adiponectin represents the most abundant protein secreted by adipose tissue (212) and adipose transcript as well as circulating levels of this protein are reduced in humans and in rodent models of obesity and T2D, as reviewed in references (27, 293, 323, 497, 645).”
Adiponectin and adiponectin receptors. (2005, background): “Moreover, plasma adiponectin levels have been shown to be decreased in patients with cardiovascular diseases (33, 34), hypertension (35), or metabolic syndrome (36).”