An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.

By L. Moerlooze, B. Spencer‐Dene, J. Revest, M. Hajihosseini, I. Rosewell, C. Dickson. Development, 2000

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Reiterative signaling and patterning during mammalian tooth morphogenesis. (2000, background): “FGFs are necessary for tooth morphogenesis to proceed beyond the bud stage as shown in transgenic mice overexpressing a soluble-negative FGF receptor (Celli et al., 1998) and lacking a functional FGFR2 receptor IIIb isoform (De Moerlooze et al., 2000).”
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth (2003, background): “Specific deletion of the b exon of Fgfr2 results in a neonatal lethal phenotype, also lacking limb buds (De Moerlooze et al., 2000).”
FGF/FGFR signaling in health and disease (2020, background): “Deletion of FGF10 results in complete distal lung agenesis.(297,298) In cultured human fetal lung both FGF7 and FGF10 can induce liquid secretion and enlargement in distal tips.”