Current concepts review: Engineering principles of clinical cell-based tissue engineering

By G. Muschler, Chizu Nakamoto, L. Griffith. 2004

873 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1752088cf3a151986caf9027a1d981a955fe1d8c

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Citations in the corpus

The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration (2011, background): “Currently, many surgeons use this method to transplant bone marrow derived stem cells (BMSCs) for bone healing appli cations due to its high value and low risk and cost [130].”
Three-Dimensional Cell Culture Matrices: State of the Art (2008, background): “Nevertheless, there are also common characteristics to be considered, such as high porosity and biocompatibility.(27) In this section, we examine these common features in structural and material aspects.”
Scaffold-Free Vascular Tissue Engineering Using Bioprinting (2009, background): “Although the apoptotic pattern does not seem to be depth-dependent, it is known that diffusion of nutrients and oxygen is limited to a few hundred microns in in vitro engineered tissues [39].”
Mesenchymal stem cell homing: the devil is in the details. (2009, unknown): “…not clinically feasible in many cases due to its potentially high degree of invasiveness (e.g., into the heart or brain), and locally administered cells often die before significantly contributing to the healing response due to diffusion limitations of nutrients and oxygen (Muschler et al., 2004).”
Immunobiology of mesenchymal stem cells (2013, background): “Administration of MSCs in situ, although highly sometimes effective in both engraftment and therapy, is less clinically applicable as it is so invasive and introduces cells in a microenvironment that could be unsuitable for survival.(108) In another study, in spinocerebellar ataxia, intravenous tran”
Scaffolding in tissue engineering: general approaches and tissue-specific considerations (2008, background): “As a result, the important roles played by scaffolds in engineered tissues, as reviewed elsewhere [79, 109], are analogous to the functions of ECM in native tissues and are associated with their architectural, biological, and mechanical features (Table 1).”