Local Inflammation and Hypoxia Abolish the Protective Anticontractile Properties of Perivascular Fat in Obese Patients

By A. Greenstein, K. Khavandi, S. Withers, K. Sonoyama, O. Clancy, M. Jeziorska, I. Laing, A. Yates, P. Pemberton, R. Malik and 1 more. Circulation, 2009

603 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/1706da9907f9fa2afca5fc319eca3fe13b9eb6f3

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In Epidemiology

1. M. Donath
2. S. Shoelson
3. Jerrold M. Olefsky

Citations in the corpus

• Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure with Preserved Ejection Fraction (2017, neutral): “Loop diuretic 10 (14) 47 (49)* 52 (53)*† <0.”
• Body Fat Distribution, Incident Cardiovascular Disease, Cancer, and All-cause Mortality (2013, positive): “Visceral adipose tissue (VAT) has been cross-sectionally associated with CVD and cancer (1,2), and is correlated with smaller ectopic fat depots, including pericardial and periaortic fat, which surround the cardiovascular system and may exert local toxic effects (3).”
• Type 2 diabetes as an inflammatory disease (2011, background): “, through vascular mechanisms including enhancement of nitric oxide bioavailabilit”