Extracellular matrix dynamics in development and regenerative medicine

By William P. Daley, Sarah B. Peters, Melinda Larsen. Journal of Cell Science, 2008

982 citations recorded by the source corpus.

Subfields: Biomaterials, Cell Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/16611a2029410465526ef8bab71d130924bb2805

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Citations in the corpus

Silk fibroin biomaterials for tissue regenerations. (2013, background): “Such results are encouraging because native extracellular matrix is continuously remodeled in-vivo by synchronous proteolytic degradation via MMPs and matrix regeneration [59].”
Control of stem cell fate by physical interactions with the extracellular matrix (2009, background): “, the extracellular matrix (ECM), has on stem cell fate, with particular emphasis on the interactions of ECM ligands with cell surface receptors (Daley et al., 2008).”
Collagen-based cell migration models in vitro and in vivo. (2009, background): “Collagen-rich CM undergoes life-long remodeling and re-shaping by tissue cells uch as fibroblasts that create adhesion receptor-mediated tenion on ECM and physiologic slow proteolytic matrix turnover, a rocess that may become enhanced during wound healing or disase [4–7].”
Extracellular Matrix Degradation and Remodeling in Development and Disease (2011, background): “This higher level of ECM organization is also dynamic and subject to sustained remodeling as mediated by reciprocal interactions between the ECM and its resident cellular components (Daley et al. 2008).”
Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture (2009, background): “Cells dynamically restructure the microenvironment to release signaling molecules, allow migration, or accommodate cell function via ECM-cleaving proteins, such as metalloproteinases (MMPs), and the deposition of ECM components, both of which are regulated by integrin-mediated signaling pathways (Da”
Overview of the matrisome--an inventory of extracellular matrix constituents and functions. (2012, background): “The remodeling of ECM by these various processes has major effects on development and pathology (Daley et al. 2008; Kessenbrock et al. 2010; Lu et al. 2011).”
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, positive): “Usually, tissue engineering uses artificial ECM because it regulates many cellular behaviors, including proliferation, survival, migration and differentiation (Daley et al. 2008).”