Oxidative mechanisms in the toxicity of chromium and cadmium ions.

By S. Stohs, D. Bagchi, E. Hassoun, M. Bagchi. Journal of Environmental Pathology And Toxicology, 2000

756 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/163f53f84013dbd4cae7484ed1cce2d6fca22c15

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In Health, Toxicology and Mutagenesis

1. A. Hartwig
2. Zhushan Fu
3. Shuhua Xi
4. D. Beyersmann

In Nutrition and Dietetics

1. A. Hartwig
2. Zhushan Fu
3. Shuhua Xi
4. D. Beyersmann

Citations in the corpus

• Alleviation by calcium of cadmium-induced root growth inhibition in Arabidopsis seedlings (2005, background): “It is a suspected carcinogen in humans and is toxic to living cells even at very low concentrations (Stohs et al. 2000).”
• The effects of heavy metals on human metabolism (2019, background): “Studies have found that cadmium exposure has an inhibitory effect on the main antioxidant enzymes: glutathione reductase and superoxide dismutase (Stohs et al. 2001; Valko et al. 2006).”
• Prevalence of exposure of heavy metals and their impact on health consequences (2018, background): “It has been found after investigations that major body’s antioxidant enzymes such as glutathione reductase and superoxide dismutase are inhibited by Cd exposure.(53,54)”
• Heavy metal poisoning: the effects of cadmium on the kidney (2010, background): “This results in the generation of reactive oxygen species (ROS) (Stohs et al. 2000), and mitochondrial disruption (Tang and Shaikh 2001) with release of cytochrome c (Thevenod 2003), leading to caspase activation, causing cell death by apoptosis and necrosis (Desagher and Martinou 2000; Thevenod et ”
• Molecular and cellular mechanisms of cadmium carcinogenesis. (2003, background): “the production of hydroxyl radicals (O’Brien and Salacinski, 1998), superoxide anions, nitric oxide and hydrogen peroxide (Galan et al., 2001; Stohs et al., 2001).”
• Occurrence, physiological responses and toxicity of nickel in plants (2013, background): “Excessive Ni leads to significant increases in the concentration of hydroxyl radicals, superoxide anions, nitric oxide and hydrogen peroxide (Boominathan and Doran 2002; Stohs et al. 2001; Hao et al. 2006).”
• Influence of metal exposure on metallothionein synthesis and lipid peroxidation in two bivalve mollusks: the oyster (Crassostrea gigas) and the mussel (Mytilus edulis) (2002, background): “ROS can act on membrane lipids leading to lipid peroxidation and to the formation of MDA.”
• Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms (2008, background): “Accordingly, the induction of DNA strand breaks and chromosomal aberrations by cadmium in mammalian cells was suppressed by antioxidants and antioxidative enzymes (Ochi et al. 1987; Stohs et al. 2001; Valko et al. 2006).”