Autophagy regulates lipid metabolism
By Rajat Singh, Susmita Kaushik, Yongjun Wang, Youqing Xiang, Inna Novak, M. Komatsu, Keiji Tanaka, A. Cuervo, M. Czaja. Nature, 2009
3,790 citations recorded by the source corpus.
Subfields: Biochemistry, Epidemiology, Physiology
View Paper: https://www.semanticscholar.org/paper/15a090ce5a9f597cc4d1d4e38a908e3e48011dc4
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In Biochemistry
- G. Hotamışlıgil
- Alec C. Kimmelman
- D. Klionsky
- D. Rubinsztein
- Sovan Sarkar
- T. Walther
- David M. Sabatini
- Robert V Farese
In Epidemiology
- Beth Levine
- Guido Kroemer
- D. Klionsky
- N. Mizushima
- I. Slaninová
- V. Deretic
- Douglas R. Green
- Alec C. Kimmelman
In Physiology
- N. Mizushima
- Beth Levine
- Guido Kroemer
- D. Klionsky
- Alec C. Kimmelman
- I. Slaninová
- G. Hotamışlıgil
- Katherine R Parzych
Citations in the corpus
- Autophagy and aging. (2011, background): “…triglycerides and cholesterol accumulate in liver cells; ER stress in hepatocytes and insulin resistance Metabolic syndrome, steatohepatitis Singh et al., 2009; Yang et al., 2010 Atg7 F/F ;Alb-Cre Skeleton-muscle specific knockout of Atg7 Muscle atrophy and age-dependent decrease in…”
- Autophagy in the Cellular Energetic Balance (2011, positive): “In fact, macrolipophagy is activated by starvation and persists beyond the 6–8 hr limit established for macroautophagy-dependent proteolysis (Singh et al., 2009a).”
- Mechanisms and disease consequences of nonalcoholic fatty liver disease (2021, background): “Autophagy, a lysosomal degradative pathway described above, is especially important to catabolize lipids and proteins in maintaining cellular health in healthy and steatotic hepatocytes (Czaja, 2016; Lee et al., 2018; Singh et al., 2009).”
- Autophagy: Renovation of Cells and Tissues (2011, background): “In addition, breakdown of lipid droplets by autophagy (lipophagy) may also account for its energy-producing role, especially in the liver (Singh et al., 2009).”
- Lipotoxicity and the gut-liver axis in NASH pathogenesis. (2018, background): “Defective induction of the autophagic flux has been linked to steatosis and lipotoxicity [53].”
- CARGO RECOGNITION FAILURE IS RESPONSIBLE FOR INEFFICIENT AUTOPHAGY IN HUNTINGTON’S DISEASE (2010, background): “We recently described selective degradation of lipid droplets by macrolipophag”