A deeply knotted protein structure and how it might fold

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How researchers see this paper

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Phytochrome structure and signaling mechanisms. (2006, background): “Such knots have only been recognized relatively recently, so known examples are relatively few (76, 101).”
Polymers with spatial or topological constraints: Theoretical and computational results (2011, background): “The repeated application of these moves typically results in dramatic simplifications of the projected diagram [106, 37].”
Intricate Knots in Proteins: Function and Evolution (2006, methodology): “A reduced representation of the structure, based on the algorithm described in [1,6,36], is shown in the lower row.”
Interactome3D: adding structural details to protein networks (2013, methodology): “The pipeline produces five models for every template and checks them with KNOT 29 to identify structural knots.”
Protein knot server: detection of knots in protein structures (2007, methodology): “Tospeedup calculations, the KMT reduction scheme is used (9,11,23,24).”