The biosynthesis and functional role of cardiolipin.

By Michael Schlame, D. Rua, Miriam L. Greenberg. Progress in lipid research, 2000

806 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies. (2012, neutral): “) formation occurs [19].”
Role of cardiolipin alterations in mitochondrial dysfunction and disease. (2007, background): “The functional importance of CL probably arises from its unique ability to interact with proteins and its role in maintaining inner membrane fluidity and osmotic stability (146, 160).”
Mitochondria in Apoptosis: Bcl-2 family Members and Mitochondrial Dynamics (2011, background): “Cardiolipin is a negatively charged phospholipid, exclusively found in mitochondria , mainly in the IMM where it is important for the activity of several complexes of the respiratory chain and of some transporters (Hasler, 2011; Schlame et al., 2000; Schug and Gottlieb, 2009).”
Phospholipid biosynthesis in eukaryotes (2008, background): “In yeast DPG synthesis has been genetical ly interrupted [26].”
Enzymes of triacylglycerol synthesis and their regulation. (2004, background): “Cardiolipin is the major phospholipid of the inner mitochondrial membrane and is critical for the function of several proteins, including cytochrome oxidase; when cardiolipin is deficient, oxidative phosphorylation is diminished [80].”