Enzymes of triacylglycerol synthesis and their regulation.

By R. Coleman, Douglas P Lee. Progress in lipid research, 2004

961 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8e079e2b7cea6ca96fba29ba6831f541938a1d77

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Citations in the corpus

The interaction of hepatic lipid and glucose metabolism in liver diseases. (2012, background): “Abbreviations: ACC, acetyl-CoA carboxylase; ATF6, activating transcription factor6; AMPK, AMP-activated protein kinase; apoB-48/100, apoprotein B-48/100; BA, bile acids; CD36/FAT, fatty acid translocase; ChREBP, carbohydrate responsive element binding protein; CPT-1, carnitine palmitoyltransferase-1”
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. (2012, positive): “Notably, among the upregulated genes were two key enzymes, Agpat1 and Mogat1 , that catalyze TG biosynthesis (18).”
Transcriptome and Gene Expression Analysis of an Oleaginous Diatom Under Different Salinity Conditions (2013, positive): “The first one was acetyl-CoA carboxylase, which was considered a key enzyme that catalyzes the first rate-limiting step of fatty acid synthesis in many organisms [44].”
Triglyceride metabolism in the liver (2017, positive): “Although initially considered to mainly mediate PL synthesis (55), more recent studies have revealed their contributions to TG metabolism in adipose tissue.”
Gene networks driving bovine milk fat synthesis during the lactation cycle (2008, background): “, liver, adipose; [67]) and, despite lack of functional studies of mammary lipin, the same steps likely apply to the mammary gland.”
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. (2013, background): “Members of the GPAT/AGPAT family of enzymes localize to the ER (Coleman and Lee, 2004).”
Liver lipid metabolism. (2008, background): “In such unusual situations, PPARc expression which is usually low in liver (10–30% of expression in adipose tissue) would nevertheless be capable of selectively upregulating a subset of the lipogenic enzymes in hepatocytes, thus enhancing both lipid synthesis and accumulation leading to steatosis (C”
A comprehensive classification system for lipids11 The evaluation of this manuscript was handled by the former Editor-in-Chief Trudy Forte. Published, JLR Papers in Press, February 16, 2005. DOI 10.1194/jlr.E400004-JLR200 (2005, background): “The glycerolipid category ( Table 5 ) is dominated by the mono-, di- and tri-substituted glycerols, the most well-known being the fatty acid esters of glycerol (acylglycerols) (17, 18).”