Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR‐γ2 transcription factor and TGF‐β/BMP signaling pathways

By E. Moerman, Kui Teng, D. Lipschitz, B. Lecka-Czernik. Aging Cell, 2004

830 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Orthopedics and Sports Medicine

View Paper: https://www.semanticscholar.org/paper/13b713722e8c3594c8c1eee3e2223088b76fa035

How researchers see this paper

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In Genetics

1. Jay J Cao

In Molecular Biology

1. Jay J Cao
2. A. Stolzing
3. A. Scutt

In Orthopedics and Sports Medicine

1. Jay J Cao

Citations in the corpus

• Effects of obesity on bone metabolism (2011, background): “Second, decreased bone marrow osteoblastogenesis with aging is usually accompanied with increased marrow adipogenesis [15,16].”
• Aging of mesenchymal stem cells. (2006, background): “Mouse Xu et al. (1983) CFU (+ Spleen?)”
• Age‐related intrinsic changes in human bone‐marrow‐derived mesenchymal stem cells and their differentiation to osteoblasts (2008, background): “It has been shown with mouse marrow cells that there are age-associated differences in osteoblast differentiation and signaling (Kahn et al., 1995; Moerman et al., 2004).”