The nuclear lamina comes of age

By Y. Gruenbaum, Ayelet Margalit, Robert D. Goldman, D. Shumaker, K. Wilson. Nature reviews. Molecular cell biology, 2005

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Characterization of the Drosophila melanogaster genome at the nuclear lamina (2006, background): “Mutations in genes encoding A-type lamins and the lamina-associated protein emerin have been linked to a variety of hereditary disease”
The advantages and disadvantages of being polyploid (2005, background): “This is demonstrated by the phenotypic effects of laminar abnormalities on human healt”
Beyond the sequence: cellular organization of genome function. (2007, neutral): “…of the nuclear periphery in genome regulation has become of particular importance due to the emergence of several human diseases that are caused by mutations in the LMNA gene, which encodes lamin A and lamin C, the two major architectural proteins of the peripheral lamina (Gruenbaum et al., 2005).”
Intermediate filaments: from cell architecture to nanomechanics (2007, background): “In the nucleus, the IF system is assembled from lamins , which together with an ever increasing number of associated transmembrane and chromatin-binding proteins constitute the nuclear lamin”