Research domain criteria (RDoC): toward a new classification framework for research on mental disorders.
By T. Insel, Bruce Cuthbert, M. Garvey, R. Heinssen, D. Pine, Kevin M. Quinn, C. Sanislow, P. Wang. American Journal of Psychiatry, 2010
6,175 citations recorded by the source corpus.
Subfields: Genetics, Health, Toxicology and Mutagenesis, Philosophy
View Paper: https://www.semanticscholar.org/paper/1305d0aac3cdba2c695fc4326310966d0c2ad8b2
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
- Terrie E. Moffitt
- Avshalom Caspi
- Thomas R. Insel
- Andreas Meyer-Lindenberg
- Susan Nolen-Hoeksema
- Christos Davatzikos
- Neelroop Parikshak
- Michael Jeffrey Gandal
In Health, Toxicology and Mutagenesis
- Thomas E. Nichols
- Stephen M. Smith
- Danilo Bzdok
- James J. Gross
- Carol Worthman
- J. Belsky
- Julia Kim-Cohen
- E. Nestler
In Philosophy
- Eiko I. Fried
- D. Johnston
- Tim Dalgleish
- Anna Bevan
- Melissa J Black
- Terrie E. Moffitt
- Avshalom Caspi
- A. Cramer
Citations in the corpus
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders (2015, background): “…phenotypes to developmental trajectories are relatively unknown; model systems in many neurobiological studies are often chosen on the basis of convenience and history; and most phenotypes are based on clinical and behavioural symptomatology rather than on biological mechanism or aetiology 22–24 .”
- The Extended Process Model of Emotion Regulation: Elaborations, Applications, and Future Directions (2015, background): “They also made the important broader point that an emotion regulation perspective may be particularly well suited to a research domain criteria perspective (Insel et al., 2010) that showcases common risk factors and mechanisms that cut across traditional distinctions among mental disorders.”
- Stress and depression: old questions, new approaches (2015, background): “Nevertheless, there is widespread recognition that diagnosis-based research in depression has obscured enormous heterogeneity, which along with comorbidity, impedes precision and reproducibility of research findings [1,2].”
- Toward ICD-11: Improving the Clinical Utility of WHO's International Classification of Mental Disorders (2010, background): “This has occurred neither as rapidly nor as extensively as scientists and practitioners had hoped (Hyman, 2007; Insel et al., 2010).”
- A Heuristic for Developing Transdiagnostic Models of Psychopathology (2011, background): “First, there is growing agreement that the heterogeneous disorders in our current diagnostic system are each made up of dysfunctional versions of processes that vary along continua in the general population (Cannon & Keller, 2006; Insel et al., 2010; Regier, Narrow, Kuhl, & Kupfer, 2009).”
- Childhood adversities and first onset of psychiatric disorders in a national sample of adolescents (2012, positive): “Although our finding that internalizing disorders are best represented by separate fear and distress dimensions is consistent with previous research,(25,26) it is unclear how these dimensions will map onto the domains recently proposed in the National Institute of Mental Health research domain crite”
- The Clinical Assessment Interview for Negative Symptoms (CAINS): Final Development and Validation (2013, background): “Thus, items in the CAINS tap constructs covering approach motivation, pleasure, social engagement, and affective expression, which are also part of the NIMHResearch Domain Criteria (5, 6).”
- Mental Disorders as Causal Systems (2015, background): “Many psychopathologists favor a transdiagnostic perspective as a new paradigm for conceptualizing mental disorders (Insel et al., 2010).”
- Statistical Challenges in "Big Data" Human Neuroimaging. (2018, positive): “…imaging with advanced analysis methods in large-scale imaging studies will allow us to find population patterns that more closely map to underlying disease mechanisms and cognitive behavior, for example as proposed in the Research Domain Criteria (RDoC) paradigm in psychiatry (Insel et al. 2010).”
- Transdiagnostic Approaches to Mental Health Problems: Current Status and Future Directions (2020, positive): “The RDoC framework (Insel et al., 2010) is an epistemic infrastructure that parses mental health complexity into six supraordinate domains (see Supplementary Table S1): positive valence systems, negative valence systems, cognitive systems, systems for social process, arousal/modulatory systems, and ”
- The relation between short-term emotion dynamics and psychological well-being: A meta-analysis. (2015, background): “As such, a synthesis of this domain would directly respond to initiatives (such as the Research Domain Criteria formulated by the National Institutes of Mental Health; Insel et al., 2010) that emphasize the need to obtain more insight into the emotional mechanisms at play in mental health and disord”