β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas
By Xiaobo Xu, J. D'Hoker, G. Stangé, S. Bonné, N. Leu, Xiangwei Xiao, M. Casteele, G. Mellitzer, Z. Ling, Danny Pipeleers and 4 more. 2008
942 citations recorded by the source corpus.
Subfields: Pharmacology, Surgery
View Paper: https://www.semanticscholar.org/paper/12975fd7ec5051bcf5afa62d18108d35a0aaa686
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In Surgery
Citations in the corpus
- Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine (2011, background): “At the same time, there has been a long dispute over whether adult β cells can be differentiated from the duct”
- Tracking adult stem cells (2011, background): “More recently, it was reported that new NGN3+ progenitor cells arise near the ducts to give rise to new β-cells after another type of injury—pancreatic duct ligation (Xu et al, 2008).”
- Pancreas organogenesis: From bud to plexus to gland (2011, background): “Xu et al. (2008) demonstrated that Ngn3þ cells were induced in the duct epithelium after PDL, and thus identified a potential source of new endocrine cells in vivo.”
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis (2013, positive): “…et al , 2011), duct (Criscimanna et al , 2011; Furuyama et al , 2011; Kopp et al , 2011) and also endocrine lineages (including beta cells) (Xu et al , 2008; Criscimanna et al , 2011; Pan et al , 2013; Van de Casteele et al , 2013), suggesting the existence of a pancreas progenitor pool…”
- Origin of new glial cells in intact and injured adult spinal cord. (2010, background): “…of a tissue to an injury may differ from simply modulating the activity of the stem or progenitor cells that maintain homeostasis in the intact tissue (Dor et al., 2004; Dor and Melton, 2008; Ito et al., 2005; Levy et al., 2005; Nakagawa et al., 2007; Simon and Frisén, 2007; Xu et al., 2008).”