Spatial memory, recognition memory, and the hippocampus.

By Nicola J. Broadbent, L. R. Squire, R. E. Clark. Proceedings of the National Academy of Sciences of the United States of America, 2004

1,009 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/1259032b1ce6883da75ba787f2a393aa741d51be

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

In Neurology

Citations in the corpus

The medial temporal lobe and recognition memory. (2007, background): “…deficit (e.g., Mumby et al. 2002, Winters et al. 2004; reviewed in Mumby 2001) whereas other studies have observed impairment at long delays (Clark et al. 2000, Hammond et al. 2004), and observation of the deficit may depend on the amount of damage to the hippocampus (e.g., Broadbent et al. 2004).”
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. (2006, neutral): “Results demonstrating that the mutants also exhibit complete loss of (1) long- but not short-term memory for object recognition, a function that is partly dependent on the hippocampus (Broadbent et al., 2004), and (2) long-term memory for single trial conditioned taste aversion, which involves insul”
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. (2009, background): “Lesions of the hippocampus that encompass as little as 30%–50% of total hippocampal volume cause severe impairment on this task (Moser et al. 1993, 1995; Broadbent et al. 2004).”
The role of the human hippocampus in odor-place associative memory. (2009, background): “Squire and colleagues (Broadbent et al. 2004; Gold and Squire 2005) suggest that when hippocampal damage is less than 40% atrophy, some aspects of memory, in particular recognition memory, may be spared despite documented hippocampal damage.”
New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment (2005, background): “Two recent studies have unequivocally shown that the impairment depends on lesion size in rats (Broadbent et al., 2004) and that post-training lesions of the hippocampus are associated with retrograde, although not anterograde, amnesia in recognition memory, suggesting that the hippocampus, when fun”